The relationship between the structure and anti-AIDS activity of polyhydroxypiperidines and polyhydroxypyrrolidines

The relationship between the structure and anti-AIDS activity of polyhydroxypiperidines and polyhydroxypyrrolidines

A mathematical model has been constructed for the anti-AIDS activity of polyhydroxypiperidines and polyhydroxypyrrolidines based on a systematic search of such sets of pairs of fragments, whose presence or absence in the molecules studied considerably affects their biological activity.

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Veröffentlicht in:Mendeleev communications 1996, Vol.6 (1), p.27-29
Hauptverfasser: Makeev, Gennady M., Kumskov, Mikhail I.
Format: Artikel
Sprache:eng
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Zusammenfassung:A mathematical model has been constructed for the anti-AIDS activity of polyhydroxypiperidines and polyhydroxypyrrolidines based on a systematic search of such sets of pairs of fragments, whose presence or absence in the molecules studied considerably affects their biological activity.
ISSN:0959-9436
DOI:10.1070/MC1996v006n01ABEH000564