Omeprazole for treatment of chronic erosive esophagitis in children: A multicenter study of efficacy, safety, tolerability and dose requirements

Objectives: To determine the efficacy, safety, and tolerability of omeprazole in children and to determine the doses required to heal chronic, severe esophagitis. Study design: Open multicenter study in children aged 1 to 16 years with erosive reflux esophagitis. The healing dose of omeprazole used...

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Veröffentlicht in:The Journal of pediatrics 2000-12, Vol.137 (6), p.800-807
Hauptverfasser: Hassall, Eric, Israel, David, Shepherd, Ross, Radke, Michael, Dalväg, Agneta, Sköld, Birgitta, Junghard, Ola, Lundborg, Per
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Sprache:eng
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Zusammenfassung:Objectives: To determine the efficacy, safety, and tolerability of omeprazole in children and to determine the doses required to heal chronic, severe esophagitis. Study design: Open multicenter study in children aged 1 to 16 years with erosive reflux esophagitis. The healing dose of omeprazole used was that with which the duration of acid reflux was
ISSN:0022-3476
1097-6833
DOI:10.1067/mpd.2000.109607