Unusual complications of warfarin therapy: Skin necrosis and priapism
Skin necrosis and priapism are unusual complications of warfarin therapy. We report a teenager with warfarin-associated skin necrosis and priapism who was subsequently found to be a compound heterozygote for protein C deficiency and a heterozygote for the factor V Leiden mutation. (J Pediatr 2000;13...
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| Veröffentlicht in: | The Journal of pediatrics 2000-08, Vol.137 (2), p.266-268 |
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| container_end_page | 268 |
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| container_issue | 2 |
| container_start_page | 266 |
| container_title | The Journal of pediatrics |
| container_volume | 137 |
| creator | Zimbelman, Julie Lefkowitz, Jerry Schaeffer, Cameron Hays, Taru Manco-Johnson, Marilyn Manhalter, Christine Nuss, Rachelle |
| description | Skin necrosis and priapism are unusual complications of warfarin therapy. We report a teenager with warfarin-associated skin necrosis and priapism who was subsequently found to be a compound heterozygote for protein C deficiency and a heterozygote for the factor V Leiden mutation. (J Pediatr 2000;137:266-8) |
| doi_str_mv | 10.1067/mpd.2000.107159 |
| format | Article |
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We report a teenager with warfarin-associated skin necrosis and priapism who was subsequently found to be a compound heterozygote for protein C deficiency and a heterozygote for the factor V Leiden mutation. (J Pediatr 2000;137:266-8)</description><identifier>ISSN: 0022-3476</identifier><identifier>EISSN: 1097-6833</identifier><identifier>DOI: 10.1067/mpd.2000.107159</identifier><identifier>PMID: 10931425</identifier><identifier>CODEN: JOPDAB</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Adolescent ; Anticoagulants - adverse effects ; Biological and medical sciences ; Drug Eruptions - complications ; Drug Eruptions - etiology ; Drug Eruptions - pathology ; Drug toxicity and drugs side effects treatment ; Factor V - genetics ; Humans ; Male ; Medical sciences ; Miscellaneous (drug allergy, mutagens, teratogens...) ; Necrosis ; Pharmacology. Drug treatments ; Priapism - chemically induced ; Priapism - complications ; Protein C Deficiency - complications ; Thrombophilia - genetics ; Warfarin - adverse effects</subject><ispartof>The Journal of pediatrics, 2000-08, Vol.137 (2), p.266-268</ispartof><rights>2000 Mosby, Inc.</rights><rights>2000 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-a2352bc306a15780a0499763ebf7b058d7ccf916f7cceba0760b1a882c0ccd233</citedby><cites>FETCH-LOGICAL-c372t-a2352bc306a15780a0499763ebf7b058d7ccf916f7cceba0760b1a882c0ccd233</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0022347600957974$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1473266$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10931425$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zimbelman, Julie</creatorcontrib><creatorcontrib>Lefkowitz, Jerry</creatorcontrib><creatorcontrib>Schaeffer, Cameron</creatorcontrib><creatorcontrib>Hays, Taru</creatorcontrib><creatorcontrib>Manco-Johnson, Marilyn</creatorcontrib><creatorcontrib>Manhalter, Christine</creatorcontrib><creatorcontrib>Nuss, Rachelle</creatorcontrib><title>Unusual complications of warfarin therapy: Skin necrosis and priapism</title><title>The Journal of pediatrics</title><addtitle>J Pediatr</addtitle><description>Skin necrosis and priapism are unusual complications of warfarin therapy. We report a teenager with warfarin-associated skin necrosis and priapism who was subsequently found to be a compound heterozygote for protein C deficiency and a heterozygote for the factor V Leiden mutation. (J Pediatr 2000;137:266-8)</description><subject>Adolescent</subject><subject>Anticoagulants - adverse effects</subject><subject>Biological and medical sciences</subject><subject>Drug Eruptions - complications</subject><subject>Drug Eruptions - etiology</subject><subject>Drug Eruptions - pathology</subject><subject>Drug toxicity and drugs side effects treatment</subject><subject>Factor V - genetics</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous (drug allergy, mutagens, teratogens...)</subject><subject>Necrosis</subject><subject>Pharmacology. Drug treatments</subject><subject>Priapism - chemically induced</subject><subject>Priapism - complications</subject><subject>Protein C Deficiency - complications</subject><subject>Thrombophilia - genetics</subject><subject>Warfarin - adverse effects</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kD1PwzAQhi0EoqUws6EMrGnPdmInbKgqH1IlBugcXRxbGPIlOwX13-MolWBhOp30vKf3HkKuKSwpCLlq-mrJAMZN0jQ_IXMKuYxFxvkpmQMwFvNEihm58P4jcHkCcE5mAeI0YemcbHbt3u-xjlTX9LVVONiu9VFnom90Bp1to-FdO-wPd9HrZ9harVznrY-wraLeWeytby7JmcHa66vjXJDdw-Zt_RRvXx6f1_fbWHHJhhgZT1mpOAikqcwAIclzKbgujSwhzSqplMmpMGHqEkEKKClmGVOgVMU4X5DVdHfs4J02RWjQoDsUFIpRSBGEFKOQYhISEjdTot-Xja7-8JOBANweAfQKa-OwVdb_conkTIiA5ROmw3tfVrvCK6tbpSvrtBqKqrP_dvgBX8x8JQ</recordid><startdate>20000801</startdate><enddate>20000801</enddate><creator>Zimbelman, Julie</creator><creator>Lefkowitz, Jerry</creator><creator>Schaeffer, Cameron</creator><creator>Hays, Taru</creator><creator>Manco-Johnson, Marilyn</creator><creator>Manhalter, Christine</creator><creator>Nuss, Rachelle</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20000801</creationdate><title>Unusual complications of warfarin therapy: Skin necrosis and priapism</title><author>Zimbelman, Julie ; Lefkowitz, Jerry ; Schaeffer, Cameron ; Hays, Taru ; Manco-Johnson, Marilyn ; Manhalter, Christine ; Nuss, Rachelle</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-a2352bc306a15780a0499763ebf7b058d7ccf916f7cceba0760b1a882c0ccd233</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adolescent</topic><topic>Anticoagulants - adverse effects</topic><topic>Biological and medical sciences</topic><topic>Drug Eruptions - complications</topic><topic>Drug Eruptions - etiology</topic><topic>Drug Eruptions - pathology</topic><topic>Drug toxicity and drugs side effects treatment</topic><topic>Factor V - genetics</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Miscellaneous (drug allergy, mutagens, teratogens...)</topic><topic>Necrosis</topic><topic>Pharmacology. Drug treatments</topic><topic>Priapism - chemically induced</topic><topic>Priapism - complications</topic><topic>Protein C Deficiency - complications</topic><topic>Thrombophilia - genetics</topic><topic>Warfarin - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zimbelman, Julie</creatorcontrib><creatorcontrib>Lefkowitz, Jerry</creatorcontrib><creatorcontrib>Schaeffer, Cameron</creatorcontrib><creatorcontrib>Hays, Taru</creatorcontrib><creatorcontrib>Manco-Johnson, Marilyn</creatorcontrib><creatorcontrib>Manhalter, Christine</creatorcontrib><creatorcontrib>Nuss, Rachelle</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>The Journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zimbelman, Julie</au><au>Lefkowitz, Jerry</au><au>Schaeffer, Cameron</au><au>Hays, Taru</au><au>Manco-Johnson, Marilyn</au><au>Manhalter, Christine</au><au>Nuss, Rachelle</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Unusual complications of warfarin therapy: Skin necrosis and priapism</atitle><jtitle>The Journal of pediatrics</jtitle><addtitle>J Pediatr</addtitle><date>2000-08-01</date><risdate>2000</risdate><volume>137</volume><issue>2</issue><spage>266</spage><epage>268</epage><pages>266-268</pages><issn>0022-3476</issn><eissn>1097-6833</eissn><coden>JOPDAB</coden><abstract>Skin necrosis and priapism are unusual complications of warfarin therapy. 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| fulltext | fulltext |
| identifier | ISSN: 0022-3476 |
| ispartof | The Journal of pediatrics, 2000-08, Vol.137 (2), p.266-268 |
| issn | 0022-3476 1097-6833 |
| language | eng |
| recordid | cdi_crossref_primary_10_1067_mpd_2000_107159 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adolescent Anticoagulants - adverse effects Biological and medical sciences Drug Eruptions - complications Drug Eruptions - etiology Drug Eruptions - pathology Drug toxicity and drugs side effects treatment Factor V - genetics Humans Male Medical sciences Miscellaneous (drug allergy, mutagens, teratogens...) Necrosis Pharmacology. Drug treatments Priapism - chemically induced Priapism - complications Protein C Deficiency - complications Thrombophilia - genetics Warfarin - adverse effects |
| title | Unusual complications of warfarin therapy: Skin necrosis and priapism |
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