Unusual complications of warfarin therapy: Skin necrosis and priapism

Unusual complications of warfarin therapy: Skin necrosis and priapism

Skin necrosis and priapism are unusual complications of warfarin therapy. We report a teenager with warfarin-associated skin necrosis and priapism who was subsequently found to be a compound heterozygote for protein C deficiency and a heterozygote for the factor V Leiden mutation. (J Pediatr 2000;13...

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Veröffentlicht in:The Journal of pediatrics 2000-08, Vol.137 (2), p.266-268
Hauptverfasser: Zimbelman, Julie, Lefkowitz, Jerry, Schaeffer, Cameron, Hays, Taru, Manco-Johnson, Marilyn, Manhalter, Christine, Nuss, Rachelle
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Anticoagulants - adverse effects
Biological and medical sciences
Drug Eruptions - complications
Drug Eruptions - etiology
Drug Eruptions - pathology
Drug toxicity and drugs side effects treatment
Factor V - genetics
Humans
Male
Medical sciences
Miscellaneous (drug allergy, mutagens, teratogens...)
Necrosis
Pharmacology. Drug treatments
Priapism - chemically induced
Priapism - complications
Protein C Deficiency - complications
Thrombophilia - genetics
Warfarin - adverse effects
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Zusammenfassung:Skin necrosis and priapism are unusual complications of warfarin therapy. We report a teenager with warfarin-associated skin necrosis and priapism who was subsequently found to be a compound heterozygote for protein C deficiency and a heterozygote for the factor V Leiden mutation. (J Pediatr 2000;137:266-8)
ISSN:0022-3476
1097-6833
DOI:10.1067/mpd.2000.107159