Dermatologic diseases of the breast and nipple

Breast and nipple skin is commonly affected by various inflammatory and neoplastic processes. Despite this fact, many physicians are unaware of the spectrum of diseases that can involve this area. Because breast and nipple skin represents a cosmetically, sexually, and functionally important entity to most patients, awareness of these disease entities is invaluable. This article reviews the normal anatomy of the breast, cutaneous manifestations of neoplastic processes that can present in these areas, and common inflammatory diseases of the breast and nipple skin. (J Am Acad Dermatol 2000;43:733-51.) Learning objective: At the conclusion of this learning activity, participants should be familiar with (1) the normal anatomy of the breast, (2) common benign and malignant tumors of the breast, and (3) the spectrum and differential diagnosis of inflammatory and infectious processes involving the breast. Better understanding of dermatologic entities affecting the breast may aid in improved diagnosis of these entities as well as ensuring appropriate intervention.