Capture and isolation of tumor cells by graphene intercalated carbon film

We prepare a near-infrared responsive graphene intercalated carbon (GIC) substrate to capture and isolate tumor cells. The rough nanostructured morphology of a GIC substrate surface can enhance the interactions between cells and substrates, resulting in high efficiency capture of cells. Due to the g...

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Veröffentlicht in:Applied physics letters 2022-02, Vol.120 (6)
Hauptverfasser: Ming, Ruiqi, Yang, Senyu, Jiang, Ye, An, Chunchun, Yang, Yuhua, Diao, Dongfeng, Cao, Yuanyuan, Chen, Tongsheng, Li, Xinlei
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Sprache:eng
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Zusammenfassung:We prepare a near-infrared responsive graphene intercalated carbon (GIC) substrate to capture and isolate tumor cells. The rough nanostructured morphology of a GIC substrate surface can enhance the interactions between cells and substrates, resulting in high efficiency capture of cells. Due to the good photothermal effect of the GIC substrate, combined with the temperature sensitivity of gelatin, tumor cells can be efficiently released under near infrared light irradiation. More importantly, no foreign substances were introduced into isolated cells in the whole process, thus maintaining high vitality of cells.
ISSN:0003-6951
1077-3118
DOI:10.1063/5.0082325