Non-invasive evaluation of microcirculation and metabolic regulation using flow mediated skin fluorescence (FMSF): Technical aspects and methodology

This paper describes a new technique for noninvasive diagnostic analysis of metabolic regulation and the microcirculation. Flow Mediated Skin Fluorescence (FMSF) is based on monitoring the intensity of NADH fluorescence emitted from skin tissue on the forearm. The principles of the technique are dis...

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Veröffentlicht in:Review of scientific instruments 2019-10, Vol.90 (10)
Hauptverfasser: Katarzynska, Joanna, Lipinski, Zbigniew, Cholewinski, Tomasz, Piotrowski, Lukasz, Dworzynski, Wojciech, Urbaniak, Malgorzata, Borkowska, Anna, Cypryk, Katarzyna, Purgal, Radoslaw, Marcinek, Andrzej, Gebicki, Jerzy
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Sprache:eng
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Zusammenfassung:This paper describes a new technique for noninvasive diagnostic analysis of metabolic regulation and the microcirculation. Flow Mediated Skin Fluorescence (FMSF) is based on monitoring the intensity of NADH fluorescence emitted from skin tissue on the forearm. The principles of the technique are discussed, in particular, concerning experimental procedures and the definition and interpretation of the measured parameters. The unique features and potential avenues for development of the FMSF technique are also outlined.
ISSN:0034-6748
1089-7623
DOI:10.1063/1.5092218