High voltage-derived enhancement of electric conduction in nanogap devices for detection of prostate-specific antigen

We report a simple method of enhancing electric conductance in nanogap devices without any additional treatments, such as silver-enhancing process. The low electric conductance after selective immobilization of biofunctionalized gold nanoparticles in the gap region was greatly enhanced by repeated I...

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Veröffentlicht in:Applied physics letters 2010-07, Vol.97 (3), p.033701-033701-3
Hauptverfasser: Park, Hyung Ju, Chi, Young Shik, Choi, Insung S., Yun, Wan Soo
Format: Artikel
Sprache:eng
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Zusammenfassung:We report a simple method of enhancing electric conductance in nanogap devices without any additional treatments, such as silver-enhancing process. The low electric conductance after selective immobilization of biofunctionalized gold nanoparticles in the gap region was greatly enhanced by repeated I-V scans at relatively high voltage ranges of −5 to 5 V, which was attributed to the formation of a new conduction pathway across the gap. The higher conduction state of the nanogap device showed a very stable I-V curve, which was used as an excellent measure of the existence of prostate-specific antigen.
ISSN:0003-6951
1077-3118
DOI:10.1063/1.3464160