S 33 NMR cryogenic probe for taurine detection

With the goal of a S 33 nuclear magnetic resonance (NMR) probe applicable to in vivo NMR on taurine-biological samples, we have developed the S 33 NMR cryogenic probe, which is applicable to taurine solutions. The NMR sensitivity gain relative to a conventional broadband probe is as large as 3.5. This work suggests that improvements in the preamplifier could allow NMR measurements on 100 μ M taurine solutions, which is the level of sensitivity necessary for biological samples.