Case 19-2013: A 35-Year-Old Woman with Recurrent Goiter and Ductal Carcinoma of the Breast

A 35-year-old woman was seen in the endocrinology clinic because of recurrent goiter and breast cancer. Micronodular lesions on the gingiva and tongue were observed. Diagnostic testing was performed. Presentation of Case Dr. Giuseppe Barbesino (Medicine): A 35-year-old woman was seen in the endocrin...

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Veröffentlicht in:The New England journal of medicine 2013-06, Vol.368 (25), p.2416-2424
Hauptverfasser: Alexander, Erik K, Chan-Smutko, Gayun, Saksena, Mansi A, Popa, Ion
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Sprache:eng
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Zusammenfassung:A 35-year-old woman was seen in the endocrinology clinic because of recurrent goiter and breast cancer. Micronodular lesions on the gingiva and tongue were observed. Diagnostic testing was performed. Presentation of Case Dr. Giuseppe Barbesino (Medicine): A 35-year-old woman was seen in the endocrinology clinic of this hospital because of recurrent goiter. The patient had been well until she was 16 years of age, when bilateral thyroid nodularity developed, with normal thyroid function. Pathological examination of tissue obtained by fine-needle aspiration at another hospital reportedly showed cytologic features that were suspicious for a follicular neoplasm. Near-total thyroidectomy (100% of the right lobe and 80% of the left lobe) was performed. Postoperatively, levothyroxine was administered. Fourteen years later, a mass developed in the left side of the neck. Ultrasonography performed . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMcpc1209273