Cushing's Disease Caused by an Ectopic Pituitary Adenoma within the Sphenoid Sinus

To the Editor: Cushing's disease (pituitary-dependent adrenal hyperplasia) continues to challenge the most discerning clinicians. Delineating the cause and treating the source of the hypercortisolism are often difficult, particularly in patients who have relatively indolent tumors that mimic th...

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Veröffentlicht in:The New England journal of medicine 1985-02, Vol.312 (9), p.587-588
Hauptverfasser: Burch, Warner M, Kramer, Richard S, Kenan, Patrick D, Hammond, Charles B
Format: Artikel
Sprache:eng
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Zusammenfassung:To the Editor: Cushing's disease (pituitary-dependent adrenal hyperplasia) continues to challenge the most discerning clinicians. Delineating the cause and treating the source of the hypercortisolism are often difficult, particularly in patients who have relatively indolent tumors that mimic the pituitary production of ACTH. We recently cared for a patient with Cushing's disease in whom an incidental finding of a sphenoid nodule on CT scan of the sella turcica proved to be an ectopic pituitary adenoma. Removal of the sphenoid tumor cured the hypercortisolism. A 43-year-old white woman presented for management of obesity. During the preceding two years she had experienced . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM198502283120921