An Efficient Route to Benzene and Phenol Derivatives via Ring-Closing Olefin Metathesis

Abstract Without the formation of inseparable regioisomers, ­various substituted phenol derivatives 2 and benzene derivatives 4 were prepared through RCM-tautomerization and RCM-dehydration protocols. A new synthetic route to precursors 1 and 3 enabled efficient access to these aromatic compounds.

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Veröffentlicht in:Synlett 2007-06, Vol.2007 (10), p.1561-1564
Hauptverfasser: Yoshida, Kazuhiro, Horiuchi, Shingo, Iwadate, Noriyuki, Kawagoe, Fumihiro, Imamoto, Tsuneo
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Sprache:eng
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Zusammenfassung:Abstract Without the formation of inseparable regioisomers, ­various substituted phenol derivatives 2 and benzene derivatives 4 were prepared through RCM-tautomerization and RCM-dehydration protocols. A new synthetic route to precursors 1 and 3 enabled efficient access to these aromatic compounds.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2007-982548