Synthesis of Simple 3,4-Diarylpyrrole-2,5-dicarboxylic Acids and Lukianol A by Oxidative Condensation of 3-Arylpyruvic Acids with Ammonia

Abstract Several derivatives of 3,4-diaryl- and 3,4-diindolylpyrrole-2,5-dicarboxylic acids including lycogalic acid A and two HALOMONAS­ metabolites were synthesized by oxidative dimerization of arylpyruvic acids or arylpyruvates in the presence of ammonia. The reaction can be applied for a short synthesis of lukianol A.