An Enantioselective Organocatalytic Route to Chiral 3,6-Dihydropyridazines from Aldehydes

An Enantioselective Organocatalytic Route to Chiral 3,6-Dihydropyridazines from Aldehydes

Abstract Here we describe a highly enantioselective organocatalytic synthesis of chiral 3,6-dihydropyridazines from achiral ­starting materials which proceeds with good yield via a one-pot ­procedure.

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Veröffentlicht in:Synlett 2006-10, Vol.2006 (16), p.2548-2552
Hauptverfasser: Oelke, Alexander J., Kumarn, Sirirat, Longbottom, Deborah A., Ley, Steven V.
Format: Artikel
Sprache:eng
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Zusammenfassung:Abstract Here we describe a highly enantioselective organocatalytic synthesis of chiral 3,6-dihydropyridazines from achiral ­starting materials which proceeds with good yield via a one-pot ­procedure.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2006-951486