Chemoselective Bromination of Active Methylene and Methyne Compounds by Potassium Bromide, Hydrochloric Acid and Hydrogen Peroxide

Chemoselective Bromination of Active Methylene and Methyne Compounds by Potassium Bromide, Hydrochloric Acid and Hydrogen Peroxide

Abstract Active methylene and methyne compounds can be chemoselectively brominated in high yields using potassium ­bromide, hydrochloric acid, and hydrogen peroxide at room temperature.

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Veröffentlicht in:Synlett 2006-09, Vol.2006 (14), p.2287-2289
Hauptverfasser: Kirihara, Masayuki, Ogawa, Shiho, Noguchi, Takuya, Okubo, Kumiko, Monma, Yoshinari, Shimizu, Ikuko, Shimosaki, Ryuji, Hatano, Akihiko, Hirai, Yoshiro
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Sprache:eng
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Zusammenfassung:Abstract Active methylene and methyne compounds can be chemoselectively brominated in high yields using potassium ­bromide, hydrochloric acid, and hydrogen peroxide at room temperature.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2006-948207