A Novel and Efficient Synthesis of 6-Dialkylamino-9-benzyl-8-methoxypurines and 6-Dialkylamino-9-benzylpurin-8-ones by Reaction of Methyl N-Benzyl-N-(6-dialkylamino-5-nitropyrimidin-4-yl)glycinates with Sodium Alkoxides

A Novel and Efficient Synthesis of 6-Dialkylamino-9-benzyl-8-methoxypurines and 6-Dialkylamino-9-benzylpurin-8-ones by Reaction of Methyl N-Benzyl-N-(6-dialkylamino-5-nitropyrimidin-4-yl)glycinates with Sodium Alkoxides

Abstract A novel and simple synthesis of 6-dialkylamino-9-benz­yl-8-methoxypurines and 6-dialkylamino-9-benzylpurin-8-ones by reaction of methyl N-benzyl-N-(6-dialkylamino-5-nitropyrimidin-4-yl)glycinates with sodium alkoxides is described.

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Veröffentlicht in:Synlett 2006-06, Vol.2006 (9), p.1422-1424
Hauptverfasser: Susvilo, Inga, Brukstus, Algirdas, Tumkevicius, Sigitas
Format: Artikel
Sprache:eng
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Zusammenfassung:Abstract A novel and simple synthesis of 6-dialkylamino-9-benz­yl-8-methoxypurines and 6-dialkylamino-9-benzylpurin-8-ones by reaction of methyl N-benzyl-N-(6-dialkylamino-5-nitropyrimidin-4-yl)glycinates with sodium alkoxides is described.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2006-941566