Water-Accelerated Synthesis of Novel Bis-2,3-dihydroquinazolin-4(1H)-one Derivatives
ABSTRACT Bisdihydroquinazolinones were synthesized for the first time by a novel pseudo five-component condensation of isatoic anhydride, a primary amine, and a dialdehyde in water. Several solvents were examined for this reaction; however, in terms of reaction yield and time, water was found to be...
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| Veröffentlicht in: | Synthesis (Stuttgart) 2006-01, Vol.2006 (2), p.344-348 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | ABSTRACT
Bisdihydroquinazolinones were synthesized for the first time by a novel pseudo five-component condensation of isatoic anhydride, a primary amine, and a dialdehyde in water. Several solvents were examined for this reaction; however, in terms of reaction yield and time, water was found to be the optimum solvent. |
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| ISSN: | 0039-7881 1437-210X |
| DOI: | 10.1055/s-2005-924766 |