A Bench-Stable Organic Salt for the Benzylation of Alcohols

A Bench-Stable Organic Salt for the Benzylation of Alcohols

Abstract 2-Benzyloxy-1-methylpyridinium triflate (Bn-OPT) effects the benzylation of alcohols in the absence of acidic or basic promoters. Solutions of Bn-OPT and primary, secondary, or tertiary alcohols give rise to the corresponding benzyl ethers upon mild heating. Acid scavengers are generally in...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Synlett 2005-12, Vol.2005 (20), p.3142-3144
Hauptverfasser: Poon, Kevin W., House, Sarah E., Dudley, Gregory B.
Format: Artikel
Sprache:eng
Schlagworte:
letter
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Abstract 2-Benzyloxy-1-methylpyridinium triflate (Bn-OPT) effects the benzylation of alcohols in the absence of acidic or basic promoters. Solutions of Bn-OPT and primary, secondary, or tertiary alcohols give rise to the corresponding benzyl ethers upon mild heating. Acid scavengers are generally included in the reaction mixture. Bn-OPT is crystalline and bench-stable.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2005-921898