Efficient One-Pot Synthesis of 1-Aryl 1,2,3-Triazoles from Aryl Halides and Terminal Alkynes in the Presence of Sodium Azide

Efficient One-Pot Synthesis of 1-Aryl 1,2,3-Triazoles from Aryl Halides and Terminal Alkynes in the Presence of Sodium Azide

Abstract An efficient one-pot synthesis of 1-aryl 1,2,3-triazoles from aryl bromides/iodides and terminal alkynes in the presence of sodium azide is described. In the case of aryl iodides, the reactions proceeded at room temperature. The reactions normally gave high yields.

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Veröffentlicht in:Synlett 2005-12, Vol.2005 (19), p.2941-2947
Hauptverfasser: Andersen, Jacob, Bolvig, Simon, Liang, Xifu
Format: Artikel
Sprache:eng
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Zusammenfassung:Abstract An efficient one-pot synthesis of 1-aryl 1,2,3-triazoles from aryl bromides/iodides and terminal alkynes in the presence of sodium azide is described. In the case of aryl iodides, the reactions proceeded at room temperature. The reactions normally gave high yields.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2005-921887