‘In situ’ Generated ‘HCl’ - An Efficient Catalyst for Solvent-Free Hantzsch Reaction at Room Temperature: Synthesis of New Dihydropyridine Glycoconjugates

ABSTRACT HCl, generated in situ from 2,4,6-trichloro[1,3,5]triazine (TCT, cyanuric chloride), catalyzed a solvent free Hantzsch reaction at room temperature with enhanced reaction rates. The reaction conditions allow facile preparation of glycoconjugates of dihydropyridines under mild reaction condi...

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Veröffentlicht in:Synthesis (Stuttgart) 2006, Vol.2006 (1), p.55-58
Hauptverfasser: Sharma, G. V., Reddy, K. Laxmi, Lakshmi, P. Sree, Krishna, Palakodety Radha
Format: Artikel
Sprache:eng
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Zusammenfassung:ABSTRACT HCl, generated in situ from 2,4,6-trichloro[1,3,5]triazine (TCT, cyanuric chloride), catalyzed a solvent free Hantzsch reaction at room temperature with enhanced reaction rates. The reaction conditions allow facile preparation of glycoconjugates of dihydropyridines under mild reaction conditions in high yields.
ISSN:0039-7881
1437-210X
DOI:10.1055/s-2005-921744