Ru-SYNPHOS® and Ru-DIFLUORPHOS®: Highly Efficient Catalysts for Practical Preparation of β-Hydroxy Amides

Ru-SYNPHOS® and Ru-DIFLUORPHOS®: Highly Efficient Catalysts for Practical Preparation of β-Hydroxy Amides

Abstract Ru-SYNPHOS ® and Ru-DIFLUORPHOS ® catalysts were efficiently used for the synthesis of a wide variety of chiral β-hydroxy amides via asymmetric hydrogenation of the corresponding β-keto amides.

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Veröffentlicht in:Synlett 2005-10, Vol.2005 (16), p.2478-2482
Hauptverfasser: Touati, Ridha, Gmiza, Thouraya, Jeulin, Séverine, Deport, Coralie, Ratovelomanana-Vidal, Virginie, Ben Hassine, Béchir, Genet, Jean-Pierre
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Sprache:eng
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Zusammenfassung:Abstract Ru-SYNPHOS ® and Ru-DIFLUORPHOS ® catalysts were efficiently used for the synthesis of a wide variety of chiral β-hydroxy amides via asymmetric hydrogenation of the corresponding β-keto amides.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2005-917089