Synthesis of 7,8-Benzo-3-hydroxy-9-azabicyclo[3.3.1]non-3-enes by Cyclocondensation of 1,3-Bis-Silyl Enol Ethers with Isoquinolines

Abstract Several functionalized 7,8-benzo-3-hydroxy-9-azabicyclo[3.3.1]non-3-enes were prepared by two-step cyclocondensation of 1,3-bis-silyl enol ethers with isoquinolinium salts.

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Veröffentlicht in:Synlett 2005-10, Vol.2005 (16), p.2489-2491
Hauptverfasser: Schmidt, Andreas, Gütlein, Jörg-Peter, Preuss, Anja, Albrecht, Uwe, Reinke, Helmut, Langer, Peter
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Sprache:eng
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Zusammenfassung:Abstract Several functionalized 7,8-benzo-3-hydroxy-9-azabicyclo[3.3.1]non-3-enes were prepared by two-step cyclocondensation of 1,3-bis-silyl enol ethers with isoquinolinium salts.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2005-872675