Synthesis of 4-Dialkylamino-6-Trifluoromethyl-5,6-dihydro-2-pyridinones via Cyclization of Enamines with α-Chloro-β,β,β-trifluoroethylisocyanates

ABSTRACT The interaction of α-chloro-β,β,β-trifluoroethylisocyanates with ‘push-pull’ enamines having a methyl group at the α-position was investigated. As a result, a set of 4-dialkylamino-6-trifluoromethyl-5,6-dihydro-2-pyridinones was obtained. Structural sensitivity of the reaction was found and...

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Veröffentlicht in:	Synthesis (Stuttgart) 2004-09, Vol.2004 (13), p.2196-2204
Hauptverfasser:	Volochnyuk, Dmitriy M., Kostyuk, Aleksandr N., Bol’but, Andrei V., Sibgatulin, Dmitriy A., Kuklya, Andrei S., Vovk, Mikhail V.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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