Synthesis of 4-Dialkylamino-6-Trifluoromethyl-5,6-dihydro-2-pyridinones via Cyclization of Enamines with α-Chloro-β,β,β-trifluoroethylisocyanates

Synthesis of 4-Dialkylamino-6-Trifluoromethyl-5,6-dihydro-2-pyridinones via Cyclization of Enamines with α-Chloro-β,β,β-trifluoroethylisocyanates

ABSTRACT The interaction of α-chloro-β,β,β-trifluoroethylisocyanates with ‘push-pull’ enamines having a methyl group at the α-position was investigated. As a result, a set of 4-dialkylamino-6-trifluoromethyl-5,6-dihydro-2-pyridinones was obtained. Structural sensitivity of the reaction was found and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Synthesis (Stuttgart) 2004-09, Vol.2004 (13), p.2196-2204
Hauptverfasser: Volochnyuk, Dmitriy M., Kostyuk, Aleksandr N., Bol’but, Andrei V., Sibgatulin, Dmitriy A., Kuklya, Andrei S., Vovk, Mikhail V.
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:ABSTRACT The interaction of α-chloro-β,β,β-trifluoroethylisocyanates with ‘push-pull’ enamines having a methyl group at the α-position was investigated. As a result, a set of 4-dialkylamino-6-trifluoromethyl-5,6-dihydro-2-pyridinones was obtained. Structural sensitivity of the reaction was found and discussed.
ISSN:0039-7881
1437-210X
DOI:10.1055/s-2004-831165