Clinical Picture of Severe Hyponatremia in Patients with Hypopituitarism Including Secondary Adrenal Insufficiency

Severe hyponatremia due to hypopituitarism and adrenal insufficiency can be life-threatening, and glucocorticoid treatment is very effective once a diagnosis of the underlying disorder has been reached. In our experience, the diagnosis of hypopituitarism in hyponatremic patients is often overlooked. In a retrospective study, we screened the files of 185 patients with severe hyponatremia (