Optimized Synthesis of an Orthogonally Protected Glucosamine
Abstract Glucosamine hydrochloride was transformed into an orthogonally protected intermediate in seven steps and 34% overall yield. The synthesis includes an optimized preparation of N-phthaloyl-β-D-glucosamine tetraacetate, a commonly used precursor in carbohydrate chemistry.
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Veröffentlicht in: | Synthesis (Stuttgart) 2002, Vol.2002 (4), p.487-490 |
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container_end_page | 490 |
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container_issue | 4 |
container_start_page | 487 |
container_title | Synthesis (Stuttgart) |
container_volume | 2002 |
creator | Hernández-Torres, Jesús M. Liew, Siong-Tern Achkar, Jihane Wei, Alexander |
description | Abstract
Glucosamine hydrochloride was transformed into an orthogonally protected intermediate in seven steps and 34% overall yield. The synthesis includes an optimized preparation of N-phthaloyl-β-D-glucosamine tetraacetate, a commonly used precursor in carbohydrate chemistry. |
doi_str_mv | 10.1055/s-2002-20962 |
format | Article |
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Glucosamine hydrochloride was transformed into an orthogonally protected intermediate in seven steps and 34% overall yield. The synthesis includes an optimized preparation of N-phthaloyl-β-D-glucosamine tetraacetate, a commonly used precursor in carbohydrate chemistry.</description><issn>0039-7881</issn><issn>1437-210X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNptj0tLxDAUhYMoWEd3_oDuNZpH0we4kcEZhYEKKrgLaXpjO7TNkGQW9debcVy6OXdxPi7nQ-iakjtKhLj3mBHCYlQ5O0EJzXiBGSWfpyghhFe4KEt6ji683xJCCsarBD3Uu9CP_Te06ds8hQ5871NrUjWltQud_bKTGoY5fXU2gA4RWw97bb0a-wku0ZlRg4erv7tAH6un9-Uz3tTrl-XjBmuWVwGXggMUeZk1TFdVHMJZ1vJGaGOgiNmCUByoLgTnmWgyo3PGY5HRRrUm4gt0e_yrnfXegZE714_KzZISeTCXXh7M5a95xG-OeOh6GEFu7d5FC_8__QPMY1mf</recordid><startdate>2002</startdate><enddate>2002</enddate><creator>Hernández-Torres, Jesús M.</creator><creator>Liew, Siong-Tern</creator><creator>Achkar, Jihane</creator><creator>Wei, Alexander</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>2002</creationdate><title>Optimized Synthesis of an Orthogonally Protected Glucosamine</title><author>Hernández-Torres, Jesús M. ; Liew, Siong-Tern ; Achkar, Jihane ; Wei, Alexander</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c269t-853ee7684b2c99039324d3b5cffe75cfde5a3e1c753345b4fc62375c41badf393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hernández-Torres, Jesús M.</creatorcontrib><creatorcontrib>Liew, Siong-Tern</creatorcontrib><creatorcontrib>Achkar, Jihane</creatorcontrib><creatorcontrib>Wei, Alexander</creatorcontrib><collection>CrossRef</collection><jtitle>Synthesis (Stuttgart)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hernández-Torres, Jesús M.</au><au>Liew, Siong-Tern</au><au>Achkar, Jihane</au><au>Wei, Alexander</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Optimized Synthesis of an Orthogonally Protected Glucosamine</atitle><jtitle>Synthesis (Stuttgart)</jtitle><addtitle>Synthesis</addtitle><date>2002</date><risdate>2002</risdate><volume>2002</volume><issue>4</issue><spage>487</spage><epage>490</epage><pages>487-490</pages><issn>0039-7881</issn><eissn>1437-210X</eissn><abstract>Abstract
Glucosamine hydrochloride was transformed into an orthogonally protected intermediate in seven steps and 34% overall yield. The synthesis includes an optimized preparation of N-phthaloyl-β-D-glucosamine tetraacetate, a commonly used precursor in carbohydrate chemistry.</abstract><doi>10.1055/s-2002-20962</doi><tpages>4</tpages></addata></record> |
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title | Optimized Synthesis of an Orthogonally Protected Glucosamine |
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