Regioselective Hydroxylation of 2,4-Lutidine: A Practical Synthesis of 4-Hydroxymethyl-2-methylpyridine
Abstract A practical synthesis of 4-hydroxymethyl-2-methylpyridine has been developed which makes use of Evans’ regioselective lithiation of readily available 2,4-lutidine and trapping with dimethylformamide.
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Veröffentlicht in: | Synthesis (Stuttgart) 2002, Vol.2002 (4), p.483-486 |
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container_end_page | 486 |
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container_issue | 4 |
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container_title | Synthesis (Stuttgart) |
container_volume | 2002 |
creator | Ragan, John A. Jones, Brian P. Meltz, Clifford N. Teixeira, John J. |
description | Abstract
A practical synthesis of 4-hydroxymethyl-2-methylpyridine has been developed which makes use of Evans’ regioselective lithiation of readily available 2,4-lutidine and trapping with dimethylformamide. |
doi_str_mv | 10.1055/s-2002-20960 |
format | Article |
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A practical synthesis of 4-hydroxymethyl-2-methylpyridine has been developed which makes use of Evans’ regioselective lithiation of readily available 2,4-lutidine and trapping with dimethylformamide.</description><issn>0039-7881</issn><issn>1437-210X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNptkE1LAzEQhoMoWKs3f8DebXSS3c1uvJVirVBQ_ABvIU0mbcp2tyRbcf-924-jl5mBed5heAi5ZXDPIM8fIuUAvC9SwBkZsCwtKGfwfU4GAKmkRVmyS3IV4xoACp7KAVm-49I3ESs0rf_BZNbZ0Px2lW59UyeNS_goo_Nd662v8TEZJ29B96TRVfLR1e0Ko497LKOn5AbbVVdRTo_DtguH6DW5cLqKeHPqQ_I1ffqczOj89fllMp5Tw4VsqWXMiMxirqWTEkQGRljDURpmF0W5YMgFFOBErm3JpcDMaJ72S144LlyaDsnoeNeEJsaATm2D3-jQKQZqL0lFtZekDpJ6_O6ItyuPG1TrZhfq_r__6T93p2jU</recordid><startdate>2002</startdate><enddate>2002</enddate><creator>Ragan, John A.</creator><creator>Jones, Brian P.</creator><creator>Meltz, Clifford N.</creator><creator>Teixeira, John J.</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>2002</creationdate><title>Regioselective Hydroxylation of 2,4-Lutidine: A Practical Synthesis of 4-Hydroxymethyl-2-methylpyridine</title><author>Ragan, John A. ; Jones, Brian P. ; Meltz, Clifford N. ; Teixeira, John J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c269t-d11c64de5a9f990640c6dc2e9c1db78b1e26070f65ad8296e4ca23c1d27f26f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ragan, John A.</creatorcontrib><creatorcontrib>Jones, Brian P.</creatorcontrib><creatorcontrib>Meltz, Clifford N.</creatorcontrib><creatorcontrib>Teixeira, John J.</creatorcontrib><collection>CrossRef</collection><jtitle>Synthesis (Stuttgart)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ragan, John A.</au><au>Jones, Brian P.</au><au>Meltz, Clifford N.</au><au>Teixeira, John J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Regioselective Hydroxylation of 2,4-Lutidine: A Practical Synthesis of 4-Hydroxymethyl-2-methylpyridine</atitle><jtitle>Synthesis (Stuttgart)</jtitle><addtitle>Synthesis</addtitle><date>2002</date><risdate>2002</risdate><volume>2002</volume><issue>4</issue><spage>483</spage><epage>486</epage><pages>483-486</pages><issn>0039-7881</issn><eissn>1437-210X</eissn><abstract>Abstract
A practical synthesis of 4-hydroxymethyl-2-methylpyridine has been developed which makes use of Evans’ regioselective lithiation of readily available 2,4-lutidine and trapping with dimethylformamide.</abstract><doi>10.1055/s-2002-20960</doi><tpages>4</tpages></addata></record> |
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source | Thieme Connect Journals |
title | Regioselective Hydroxylation of 2,4-Lutidine: A Practical Synthesis of 4-Hydroxymethyl-2-methylpyridine |
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