Rare Earth Salt Catalyzed Asymmetric Diels-Alder Reaction with a Chiral Dienophile in Supercritical Carbon Dioxide: Enhancement Effect on Stereoselectivity
Abstract The rare earth(III) salt catalyzed asymmetric Diels-Alder reaction of cyclopentadiene with a chiral dienophile in supercritical carbon dioxide (scCO 2 ) proceeded rapidly to give the adduct with a higher diastereoselectivity than that in dichloromethane; optimization of the CO 2 density inc...
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| Veröffentlicht in: | Synlett 2002-01, Vol.2002 (1), p.134-136 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Abstract
The rare earth(III) salt catalyzed asymmetric Diels-Alder reaction of cyclopentadiene with a chiral dienophile in supercritical carbon dioxide (scCO
2
) proceeded rapidly to give the adduct with a higher diastereoselectivity than that in dichloromethane; optimization of the CO
2
density increased the de value up to 77%. |
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| ISSN: | 0936-5214 1437-2096 |
| DOI: | 10.1055/s-2002-19348 |