Electronic Tuning in C1-Symmetric Chelating Diphosphane Ligands Supported on Stereogenic Aryl-Heteroaryl Templates

Abstract The syntheses of a wide range of novel C 1 -symmetric chelating diphosphanes with stereogenic axes are reported. These ligands feature identical or different phosphanyl groups supported on diverse atropisomeric templates based on the interconnection of five-membered heteroaromatic and six-membered carbocyclic rings. Easy synthetic accessibility, independent tunability of the electronic and steric properties of the two phosphane donors, the low cost and the good stereoselection ability of some of them obtained in an enantiopure state are the main advantageous features of this class of ligands.