Antioxidant Activity of Leaves of Salvia Species in Enzyme-Dependent and Enzyme-Independent Systems of Lipid Peroxidation and their Phenolic Constituents

Abstract The protective effects of eleven SALVIA species native to Europe against enzyme-dependent and enzyme-independent lipid peroxidation were evaluated. The 50 % aqueous methanolic extracts of the leaves of all tested plants were found to be more effective than the positive control α-tocopherol...

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Veröffentlicht in:	Planta medica 2001-06, Vol.67 (4), p.366-368
Hauptverfasser:	Zupkó, István, Hohmann, Judit, Rédei, Dóra, Falkay, György, Janicsák, Gábor, Máthé, Imre
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - isolation & purification Antioxidants - pharmacology Biological and medical sciences Brain - drug effects Brain - enzymology Cattle Cinnamates - isolation & purification Cinnamates - pharmacology Coumaric Acids - isolation & purification Coumaric Acids - pharmacology Depsides Dose-Response Relationship, Drug Flavonoids - isolation & purification Flavonoids - pharmacology General pharmacology Letter Lipid Peroxidation - drug effects Medical sciences Microsomes, Liver - drug effects Microsomes, Liver - enzymology Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Leaves - chemistry Plants, Medicinal - chemistry Rats Rosmarinic Acid Structure-Activity Relationship Tocopherols Vitamin E - analogs & derivatives Vitamin E - pharmacology
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Zusammenfassung:	Abstract The protective effects of eleven SALVIA species native to Europe against enzyme-dependent and enzyme-independent lipid peroxidation were evaluated. The 50 % aqueous methanolic extracts of the leaves of all tested plants were found to be more effective than the positive control α-tocopherol acid succinate. The extracts of S. CANDELABRUM, S. RINGENS, S. TOMENTOSA, S. NEMOROSA, and S. GLUTINOSA displayed considerable concentration-dependent antioxidative effects that were comparable to those of the medicinal and aromatic plant S. OFFICINALIS. The concentrations of flavonoids, hydroxycinnamic acids and total phenolic compounds in each extract were quantified with the aim of clarifying the connection between activity and chemical composition.
ISSN:	0032-0943 1439-0221
DOI:	10.1055/s-2001-14327