Anti-Inflammatory Activity of Coumarins from Decatropis bicolor on TPA Ear Mice Model

Abstract From the aerial parts of DECATROPIS BICOLOR, heraclenin (1), seselin (2), psoralen (3), imperatorin (4), skimmianine (5), and heraclenol (6), were isolated. This is the first time that coumarin-like compounds are isolated from DECATROPIS genus. The anti-inflammatory properties of compounds...

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Veröffentlicht in:Planta medica 2000-04, Vol.66 (3), p.279-281
Hauptverfasser: García-Argáez, Aída N., Ramírez Apan, Teresa O., Delgado, Hortensia Parra, Velázquez, Guillermo, Martínez-Vázquez, Mariano
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container_issue 3
container_start_page 279
container_title Planta medica
container_volume 66
creator García-Argáez, Aída N.
Ramírez Apan, Teresa O.
Delgado, Hortensia Parra
Velázquez, Guillermo
Martínez-Vázquez, Mariano
description Abstract From the aerial parts of DECATROPIS BICOLOR, heraclenin (1), seselin (2), psoralen (3), imperatorin (4), skimmianine (5), and heraclenol (6), were isolated. This is the first time that coumarin-like compounds are isolated from DECATROPIS genus. The anti-inflammatory properties of compounds 1 - 6 were examined against the ear edema in mice produced by TPA. The results suggest that the anti-inflammatory activity of each compound depends of its individual substitution on the aromatic ring rather than the coumarin skeleton itself.
doi_str_mv 10.1055/s-2000-14894
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title Anti-Inflammatory Activity of Coumarins from Decatropis bicolor on TPA Ear Mice Model
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