Anti-Inflammatory Activity of Coumarins from Decatropis bicolor on TPA Ear Mice Model
Abstract From the aerial parts of DECATROPIS BICOLOR, heraclenin (1), seselin (2), psoralen (3), imperatorin (4), skimmianine (5), and heraclenol (6), were isolated. This is the first time that coumarin-like compounds are isolated from DECATROPIS genus. The anti-inflammatory properties of compounds...
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| Veröffentlicht in: | Planta medica 2000-04, Vol.66 (3), p.279-281 |
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| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | Abstract
From the aerial parts of DECATROPIS BICOLOR, heraclenin
(1), seselin (2), psoralen (3), imperatorin (4), skimmianine
(5), and heraclenol (6), were
isolated. This is the first time that coumarin-like compounds are isolated
from DECATROPIS genus. The anti-inflammatory properties
of compounds 1 - 6 were examined
against the ear edema in mice produced by TPA. The results suggest that the
anti-inflammatory activity of each compound depends of its individual substitution
on the aromatic ring rather than the coumarin skeleton itself. |
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| ISSN: | 0032-0943 1439-0221 |
| DOI: | 10.1055/s-2000-14894 |