Recent Advances in Copper-Catalyzed Radical C–H Bond Activation Using N–F Reagents

Abstract This Short Review is aimed at giving an update in the area of copper-catalyzed C–H functionalization involving nitrogen-centered radicals generated from substrates containing N–F bonds. These processes include intermolecular Csp 3 –H bond functionalization, remote Csp 3 –H bond functionalization via intramolecular hydrogen atom transfer (HAT), and Csp 2 –H bond functionalization, which might be of potential use in industrial applications in the future. 1 Introduction 2 Intermolecular Csp 3 –H Functionalization 3 Remote Csp 3 –H Functionalization 4 Csp 2 –H Functionalization 5 Conclusion