Synthesis of (R)-Lactic Acid and (2R,5R)-2-tert-Butyl-5-methyl-1,3-dioxolan-4-one

Abstract A convenient procedure for the synthesis of very expensive ( R )-lactic acid from relatively inexpensive ( R )-alanine is described. Its subsequent conversion into a chiral dioxolanone can be carried out by using an inexpensive pivalaldehyde– tert -butanol mixture.

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Veröffentlicht in:	Synthesis (Stuttgart) 2015-06, Vol.47 (11), p.1557-1559
Hauptverfasser:	Aitken, R. Alan, Meehan, Anna, Power, Lynn A.
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Sprache:	eng
Schlagworte:	psp
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description	Abstract A convenient procedure for the synthesis of very expensive ( R )-lactic acid from relatively inexpensive ( R )-alanine is described. Its subsequent conversion into a chiral dioxolanone can be carried out by using an inexpensive pivalaldehyde– tert -butanol mixture.
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title	Synthesis of (R)-Lactic Acid and (2R,5R)-2-tert-Butyl-5-methyl-1,3-dioxolan-4-one
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