Iron-Catalyzed Oxidative Coupling of Benzylamines and Indoles: Novel Approach for Synthesis of Bis(indolyl)methanes

Iron-Catalyzed Oxidative Coupling of Benzylamines and Indoles: Novel Approach for Synthesis of Bis(indolyl)methanes

Abstract A novel route for synthesis of bis(indolyl)methanes has been developed by the oxidative coupling of benzylamines and indoles in the presence of iron(II) triflate as a catalyst and molecular oxygen as an oxidant. This method promises versatility, cost-effectiveness, and efficiency.

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Veröffentlicht in:Synthesis (Stuttgart) 2015-06, Vol.47 (12), p.1766-1774
Hauptverfasser: Gopalaiah, Kovuru, Chandrudu, Sankala Naga, Devi, Alka
Format: Artikel
Sprache:eng
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Zusammenfassung:Abstract A novel route for synthesis of bis(indolyl)methanes has been developed by the oxidative coupling of benzylamines and indoles in the presence of iron(II) triflate as a catalyst and molecular oxygen as an oxidant. This method promises versatility, cost-effectiveness, and efficiency.
ISSN:0039-7881
1437-210X
DOI:10.1055/s-0034-1380012