A New Enantioselective Synthesis of the Anti-Parkinson Agent Safinamide
Abstract An alternative highly enantioselective synthesis of the anti-Parkinson agent safinamide from simple, commercially available, starting materials is described. The protocol might also be useful in the synthesis of structural variants of safinamide, such as ralfinamide or related analogues
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Veröffentlicht in: | Synthesis (Stuttgart) 2014-07, Vol.46 (13), p.1751-1756 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | Abstract
An alternative highly enantioselective synthesis of the anti-Parkinson agent safinamide from simple, commercially available, starting materials is described. The protocol might also be useful in the synthesis of structural variants of safinamide, such as ralfinamide or related analogues |
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ISSN: | 0039-7881 1437-210X |
DOI: | 10.1055/s-0033-1341104 |