A New Enantioselective Synthesis of the Anti-Parkinson Agent Safinamide

Abstract An alternative highly enantioselective synthesis of the anti-Parkinson agent safinamide from simple, commercially available, starting materials is described. The protocol might also be useful in the synthesis of structural variants of safinamide, such as ralfinamide or related analogues

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Veröffentlicht in:Synthesis (Stuttgart) 2014-07, Vol.46 (13), p.1751-1756
Hauptverfasser: Reddi, Anjaneyulu, Mujahid, Mohammad, Sasikumar, Murugesan, Muthukrishnan, Murugan
Format: Artikel
Sprache:eng
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Zusammenfassung:Abstract An alternative highly enantioselective synthesis of the anti-Parkinson agent safinamide from simple, commercially available, starting materials is described. The protocol might also be useful in the synthesis of structural variants of safinamide, such as ralfinamide or related analogues
ISSN:0039-7881
1437-210X
DOI:10.1055/s-0033-1341104