Arterial Infusion Chemotherapy in the Treatment of Isolated Hepatic Colorectal Metastases

ABSTRACT Colorectal carcinoma is a common malignancy with a significant percentage of patients developing or presenting with isolated hepatic metastases. Disappointing results from peripheral intravenous chemotherapy have led to the development and utilization of intra-arterial chemoinfusion as a treatment modality in these patients. This article describes techniques and potential complications associated with the percutaneous and surgical placement of hepatic arterial infusion catheters for treatment of patients with isolated hepatic metastases from colorectal carcinoma.