Preparation of 4-Arylthiazol-2(3H)-ones and the Three-Component Synthesis of Multidentate 5,5′-Methylenebis[4-arylthiazol-2(3H)-one] Ligands

Preparation of 4-Arylthiazol-2(3H)-ones and the Three-Component Synthesis of Multidentate 5,5′-Methylenebis[4-arylthiazol-2(3H)-one] Ligands

Abstract The synthesis of 4-arylthiazol-2(3 H )-ones is reported employing a novel and mild methodology using benign solvents. In a second objective, the multicomponent preparation of 5,5′-methylenebis[4-arylthiazol-2(3 H )-ones] is described following the same strategy. The analysis of the mechanis...

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Veröffentlicht in:Synthesis (Stuttgart) 2023-01, Vol.55 (1), p.141-149
Hauptverfasser: Ortuño, Juan F., Poyraz, Samet, Belabbes, Asmaa, Kavas, Özge, Belveren, Samet, Altuğ, Cevher, Retamosa, María de Gracia, Foubelo, Francisco, Pask, Christopher M., Sansano, José M., Döndaş, H. Ali
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Sprache:eng
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Zusammenfassung:Abstract The synthesis of 4-arylthiazol-2(3 H )-ones is reported employing a novel and mild methodology using benign solvents. In a second objective, the multicomponent preparation of 5,5′-methylenebis[4-arylthiazol-2(3 H )-ones] is described following the same strategy. The analysis of the mechanism is also studied and confirmed using chemical tests.
ISSN:0039-7881
1437-210X
DOI:10.1055/a-1930-6840