Trimethylsilyl Esters as Novel Dual-Purpose Protecting Reagents

Trimethylsilyl Esters as Novel Dual-Purpose Protecting Reagents

Abstract Trimethylsilyl esters, AcOTMS, BzOTMS, TCAOTMS, etc., are inexpensive and chemically stable reagents that pose a negligible environmental hazard. Such compounds prove to serve as efficient dual-purpose reagents to respectively achieve acylation and trimethylsilylation of alcohols under acid...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Synthesis (Stuttgart) 2022-02, Vol.54 (3), p.754-762
Hauptverfasser: Chen, Jyun-Siao, Huang, Po-Hsun, Hsieh, Ya-Chi, Liu, Jen-Wei, Hsu, Hsiao-Lin, Zhang, Kai-Min, Wu, Ren-Tsung, Chang, Ting-Shuo, Liu, Yu-Hao, Wu, Hsin-Ru, Luo, Shun-Yuan
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Abstract Trimethylsilyl esters, AcOTMS, BzOTMS, TCAOTMS, etc., are inexpensive and chemically stable reagents that pose a negligible environmental hazard. Such compounds prove to serve as efficient dual-purpose reagents to respectively achieve acylation and trimethylsilylation of alcohols under acidic or basic conditions. Herein, a detailed study on protection of various substrates and new methodological investigations is described.
ISSN:0039-7881
1437-210X
DOI:10.1055/a-1654-2211