The regulation of haemoglobin synthesis in cultured chick blastoderms by steroids related to 5β-androstane

The regulation of haemoglobin synthesis in cultured chick blastoderms by steroids related to 5β-androstane

1. After 24h of incubation, the blastoderm may be dissected from the early developing chick embryo and successfully maintained under conditions of organ culture in vitro. 2. Low concentrations of steroids related to 5beta-androstane stimulate the synthesis of foetal haemoglobins, types E and P, in a...

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Veröffentlicht in:Biochemical journal 1976-01, Vol.154 (1), p.81-93
Hauptverfasser: Irving, R A, Mainwaring, W I P, Spooner, P M
Format: Artikel
Sprache:eng
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Zusammenfassung:1. After 24h of incubation, the blastoderm may be dissected from the early developing chick embryo and successfully maintained under conditions of organ culture in vitro. 2. Low concentrations of steroids related to 5beta-androstane stimulate the synthesis of foetal haemoglobins, types E and P, in a highly steroid- and tissue-specific manner.
ISSN:0264-6021
DOI:10.1042/bj1540081