Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores

Novel organic photoCORMs based on micelle-encapsulated unsaturated cyclic α-diketones were designed and synthesized. These photoCORMs can be activated by visible light, have potentially low toxicity, allow the delivery of carbon monoxide to be monitored by fluorescence imaging techniques, and thus a...

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Veröffentlicht in:Organic & biomolecular chemistry 2013-10, Vol.11 (39), p.6671
Hauptverfasser: Peng, Ping, Wang, Chaoming, Shi, Zheng, Johns, Valentine K, Ma, Liyuan, Oyer, Jeremiah, Copik, Alicja, Igarashi, Robert, Liao, Yi
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container_end_page
container_issue 39
container_start_page 6671
container_title Organic & biomolecular chemistry
container_volume 11
creator Peng, Ping
Wang, Chaoming
Shi, Zheng
Johns, Valentine K
Ma, Liyuan
Oyer, Jeremiah
Copik, Alicja
Igarashi, Robert
Liao, Yi
description Novel organic photoCORMs based on micelle-encapsulated unsaturated cyclic α-diketones were designed and synthesized. These photoCORMs can be activated by visible light, have potentially low toxicity, allow the delivery of carbon monoxide to be monitored by fluorescence imaging techniques, and thus are useful tools for the study of the biological function of CO.
doi_str_mv 10.1039/c3ob41385c
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source MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Capsules
Carbon Monoxide - analysis
Carbon Monoxide - chemistry
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
Ketones - chemistry
Light
Micelles
title Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores
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