Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores

Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores

Novel organic photoCORMs based on micelle-encapsulated unsaturated cyclic α-diketones were designed and synthesized. These photoCORMs can be activated by visible light, have potentially low toxicity, allow the delivery of carbon monoxide to be monitored by fluorescence imaging techniques, and thus a...

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Veröffentlicht in:Organic & biomolecular chemistry 2013-10, Vol.11 (39), p.6671
Hauptverfasser: Peng, Ping, Wang, Chaoming, Shi, Zheng, Johns, Valentine K, Ma, Liyuan, Oyer, Jeremiah, Copik, Alicja, Igarashi, Robert, Liao, Yi
Format: Artikel
Sprache:eng
Schlagworte:
Capsules
Carbon Monoxide - analysis
Carbon Monoxide - chemistry
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
Ketones - chemistry
Light
Micelles
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Zusammenfassung:Novel organic photoCORMs based on micelle-encapsulated unsaturated cyclic α-diketones were designed and synthesized. These photoCORMs can be activated by visible light, have potentially low toxicity, allow the delivery of carbon monoxide to be monitored by fluorescence imaging techniques, and thus are useful tools for the study of the biological function of CO.
ISSN:1477-0520
1477-0539
DOI:10.1039/c3ob41385c