Luminescent biscarbene iridium(III) complexes as living cell imaging reagents

Five iridium(III) complexes with two N-heterocyclic carbene (NHC) ligands and an ancillary ligand have been designed and successfully synthesized. With multicolor photoluminescence and low toxicity, these carbene complexes were tested, for the first time, as living cell imaging reagents and showed p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2013-04, Vol.49 (31), p.3230
Hauptverfasser: Zhou, Yuyang, Jia, Junli, Li, Wanfei, Fei, Hao, Zhou, Ming
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue 31
container_start_page 3230
container_title Chemical communications (Cambridge, England)
container_volume 49
creator Zhou, Yuyang
Jia, Junli
Li, Wanfei
Fei, Hao
Zhou, Ming
description Five iridium(III) complexes with two N-heterocyclic carbene (NHC) ligands and an ancillary ligand have been designed and successfully synthesized. With multicolor photoluminescence and low toxicity, these carbene complexes were tested, for the first time, as living cell imaging reagents and showed promise for application beyond the OLED (organic light emitting diode) area.
doi_str_mv 10.1039/c3cc40845k
format Article
fullrecord <record><control><sourceid>pubmed_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1039_c3cc40845k</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>23482967</sourcerecordid><originalsourceid>FETCH-LOGICAL-c287t-cdfcfa6eed732c996e2f9242d8bacea49b0b4444d87f7ce6113cbd10207063fb3</originalsourceid><addsrcrecordid>eNpFkE1LxDAQhoMo7rp68QdIjipU89UmPcriR6HiRcFbSSbTJdp2l2RX9N_bZf14LzMDDy_DQ8gpZ1ecyfIaJIBiRuXve2TKZaGyXJnX_e2el5mWKp-Qo5Te2Biem0MyEVIZURZ6Sh7rTR8GTIDDmrqQwEaHA9IQgw-b_ryqqgsKy37V4ScmahPtwkcYFhSw62jo7WJ7RLSLsSAdk4PWdglPfuaMvNzdPs8fsvrpvprf1BkIo9cZ-BZaWyB6LQWUZYGiLYUS3jgLaFXpmFNjvNGtBiw4l-A8Z4JpVsjWyRm53PVCXKYUsW1WcfwlfjWcNVsnzb-TET7bwauN69H_ob8S5Dcme14n</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Luminescent biscarbene iridium(III) complexes as living cell imaging reagents</title><source>MEDLINE</source><source>Royal Society Of Chemistry Journals 2008-</source><source>Alma/SFX Local Collection</source><creator>Zhou, Yuyang ; Jia, Junli ; Li, Wanfei ; Fei, Hao ; Zhou, Ming</creator><creatorcontrib>Zhou, Yuyang ; Jia, Junli ; Li, Wanfei ; Fei, Hao ; Zhou, Ming</creatorcontrib><description>Five iridium(III) complexes with two N-heterocyclic carbene (NHC) ligands and an ancillary ligand have been designed and successfully synthesized. With multicolor photoluminescence and low toxicity, these carbene complexes were tested, for the first time, as living cell imaging reagents and showed promise for application beyond the OLED (organic light emitting diode) area.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/c3cc40845k</identifier><identifier>PMID: 23482967</identifier><language>eng</language><publisher>England</publisher><subject>Cell Line, Tumor ; Cell Survival - drug effects ; Contrast Media - chemical synthesis ; Contrast Media - chemistry ; Contrast Media - toxicity ; Coordination Complexes - chemical synthesis ; Coordination Complexes - chemistry ; Coordination Complexes - toxicity ; HeLa Cells ; Heterocyclic Compounds - chemistry ; Humans ; Iridium - chemistry ; Methane - analogs &amp; derivatives ; Methane - chemistry ; Microscopy, Fluorescence ; Temperature</subject><ispartof>Chemical communications (Cambridge, England), 2013-04, Vol.49 (31), p.3230</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c287t-cdfcfa6eed732c996e2f9242d8bacea49b0b4444d87f7ce6113cbd10207063fb3</citedby><cites>FETCH-LOGICAL-c287t-cdfcfa6eed732c996e2f9242d8bacea49b0b4444d87f7ce6113cbd10207063fb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23482967$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhou, Yuyang</creatorcontrib><creatorcontrib>Jia, Junli</creatorcontrib><creatorcontrib>Li, Wanfei</creatorcontrib><creatorcontrib>Fei, Hao</creatorcontrib><creatorcontrib>Zhou, Ming</creatorcontrib><title>Luminescent biscarbene iridium(III) complexes as living cell imaging reagents</title><title>Chemical communications (Cambridge, England)</title><addtitle>Chem Commun (Camb)</addtitle><description>Five iridium(III) complexes with two N-heterocyclic carbene (NHC) ligands and an ancillary ligand have been designed and successfully synthesized. With multicolor photoluminescence and low toxicity, these carbene complexes were tested, for the first time, as living cell imaging reagents and showed promise for application beyond the OLED (organic light emitting diode) area.</description><subject>Cell Line, Tumor</subject><subject>Cell Survival - drug effects</subject><subject>Contrast Media - chemical synthesis</subject><subject>Contrast Media - chemistry</subject><subject>Contrast Media - toxicity</subject><subject>Coordination Complexes - chemical synthesis</subject><subject>Coordination Complexes - chemistry</subject><subject>Coordination Complexes - toxicity</subject><subject>HeLa Cells</subject><subject>Heterocyclic Compounds - chemistry</subject><subject>Humans</subject><subject>Iridium - chemistry</subject><subject>Methane - analogs &amp; derivatives</subject><subject>Methane - chemistry</subject><subject>Microscopy, Fluorescence</subject><subject>Temperature</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1LxDAQhoMo7rp68QdIjipU89UmPcriR6HiRcFbSSbTJdp2l2RX9N_bZf14LzMDDy_DQ8gpZ1ecyfIaJIBiRuXve2TKZaGyXJnX_e2el5mWKp-Qo5Te2Biem0MyEVIZURZ6Sh7rTR8GTIDDmrqQwEaHA9IQgw-b_ryqqgsKy37V4ScmahPtwkcYFhSw62jo7WJ7RLSLsSAdk4PWdglPfuaMvNzdPs8fsvrpvprf1BkIo9cZ-BZaWyB6LQWUZYGiLYUS3jgLaFXpmFNjvNGtBiw4l-A8Z4JpVsjWyRm53PVCXKYUsW1WcfwlfjWcNVsnzb-TET7bwauN69H_ob8S5Dcme14n</recordid><startdate>20130421</startdate><enddate>20130421</enddate><creator>Zhou, Yuyang</creator><creator>Jia, Junli</creator><creator>Li, Wanfei</creator><creator>Fei, Hao</creator><creator>Zhou, Ming</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20130421</creationdate><title>Luminescent biscarbene iridium(III) complexes as living cell imaging reagents</title><author>Zhou, Yuyang ; Jia, Junli ; Li, Wanfei ; Fei, Hao ; Zhou, Ming</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c287t-cdfcfa6eed732c996e2f9242d8bacea49b0b4444d87f7ce6113cbd10207063fb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Cell Line, Tumor</topic><topic>Cell Survival - drug effects</topic><topic>Contrast Media - chemical synthesis</topic><topic>Contrast Media - chemistry</topic><topic>Contrast Media - toxicity</topic><topic>Coordination Complexes - chemical synthesis</topic><topic>Coordination Complexes - chemistry</topic><topic>Coordination Complexes - toxicity</topic><topic>HeLa Cells</topic><topic>Heterocyclic Compounds - chemistry</topic><topic>Humans</topic><topic>Iridium - chemistry</topic><topic>Methane - analogs &amp; derivatives</topic><topic>Methane - chemistry</topic><topic>Microscopy, Fluorescence</topic><topic>Temperature</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhou, Yuyang</creatorcontrib><creatorcontrib>Jia, Junli</creatorcontrib><creatorcontrib>Li, Wanfei</creatorcontrib><creatorcontrib>Fei, Hao</creatorcontrib><creatorcontrib>Zhou, Ming</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhou, Yuyang</au><au>Jia, Junli</au><au>Li, Wanfei</au><au>Fei, Hao</au><au>Zhou, Ming</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Luminescent biscarbene iridium(III) complexes as living cell imaging reagents</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><addtitle>Chem Commun (Camb)</addtitle><date>2013-04-21</date><risdate>2013</risdate><volume>49</volume><issue>31</issue><spage>3230</spage><pages>3230-</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>Five iridium(III) complexes with two N-heterocyclic carbene (NHC) ligands and an ancillary ligand have been designed and successfully synthesized. With multicolor photoluminescence and low toxicity, these carbene complexes were tested, for the first time, as living cell imaging reagents and showed promise for application beyond the OLED (organic light emitting diode) area.</abstract><cop>England</cop><pmid>23482967</pmid><doi>10.1039/c3cc40845k</doi></addata></record>
fulltext fulltext
identifier ISSN: 1359-7345
ispartof Chemical communications (Cambridge, England), 2013-04, Vol.49 (31), p.3230
issn 1359-7345
1364-548X
language eng
recordid cdi_crossref_primary_10_1039_c3cc40845k
source MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Cell Line, Tumor
Cell Survival - drug effects
Contrast Media - chemical synthesis
Contrast Media - chemistry
Contrast Media - toxicity
Coordination Complexes - chemical synthesis
Coordination Complexes - chemistry
Coordination Complexes - toxicity
HeLa Cells
Heterocyclic Compounds - chemistry
Humans
Iridium - chemistry
Methane - analogs & derivatives
Methane - chemistry
Microscopy, Fluorescence
Temperature
title Luminescent biscarbene iridium(III) complexes as living cell imaging reagents
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T17%3A36%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Luminescent%20biscarbene%20iridium(III)%20complexes%20as%20living%20cell%20imaging%20reagents&rft.jtitle=Chemical%20communications%20(Cambridge,%20England)&rft.au=Zhou,%20Yuyang&rft.date=2013-04-21&rft.volume=49&rft.issue=31&rft.spage=3230&rft.pages=3230-&rft.issn=1359-7345&rft.eissn=1364-548X&rft_id=info:doi/10.1039/c3cc40845k&rft_dat=%3Cpubmed_cross%3E23482967%3C/pubmed_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/23482967&rfr_iscdi=true