Luminescent biscarbene iridium(III) complexes as living cell imaging reagents

Five iridium(III) complexes with two N-heterocyclic carbene (NHC) ligands and an ancillary ligand have been designed and successfully synthesized. With multicolor photoluminescence and low toxicity, these carbene complexes were tested, for the first time, as living cell imaging reagents and showed p...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2013-04, Vol.49 (31), p.3230
Hauptverfasser:	Zhou, Yuyang, Jia, Junli, Li, Wanfei, Fei, Hao, Zhou, Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Cell Survival - drug effects Contrast Media - chemical synthesis Contrast Media - chemistry Contrast Media - toxicity Coordination Complexes - chemical synthesis Coordination Complexes - chemistry Coordination Complexes - toxicity HeLa Cells Heterocyclic Compounds - chemistry Humans Iridium - chemistry Methane - analogs & derivatives Methane - chemistry Microscopy, Fluorescence Temperature
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Beschreibung
Zusammenfassung:	Five iridium(III) complexes with two N-heterocyclic carbene (NHC) ligands and an ancillary ligand have been designed and successfully synthesized. With multicolor photoluminescence and low toxicity, these carbene complexes were tested, for the first time, as living cell imaging reagents and showed promise for application beyond the OLED (organic light emitting diode) area.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c3cc40845k