Molecularly imprinted nanotubes for enantioselective drug delivery and controlled release

Molecularly imprinted nanotubes for enantioselective drug delivery and controlled release are fabricated by the combination of template synthesis and ATRP grafting. The release of R -propranolol from the imprinted nanotubes in rats is restricted while the release of pharmacologically active S -enant...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2010-11, Vol.46 (41), p.7688-769
Hauptverfasser:	Yin, Junfa, Cui, Yue, Yang, Gengliang, Wang, Hailin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Survival - drug effects Delayed-Action Preparations - chemical synthesis Delayed-Action Preparations - chemistry Delayed-Action Preparations - pharmacokinetics Delayed-Action Preparations - toxicity Drug Carriers - chemical synthesis Drug Carriers - chemistry Drug Carriers - toxicity Hep G2 Cells Humans Models, Molecular Molecular Conformation Molecular Imprinting - methods Nanotubes - chemistry Nanotubes - toxicity Propranolol - chemistry Propranolol - pharmacokinetics Rats Stereoisomerism Substrate Specificity
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