Recent advances in Chan-Lam coupling reaction

Chan-Lam coupling is one of the most promising and versatile coupling reactions in the realm of organic chemistry. Developing environmentally benign, green, recyclable, and benchtop protocols is undoubtedly one of the most attractive areas of research. The huge potential of Chan-Lam coupling in terms of diverse carbon-heteroatom bonds, substrate libraries, and the study of new greener approaches presents enormous opportunities for future research. Herein, we discuss the recent advancements in Chan-Lam coupling as well as the anticipated future trends and prospects. Chan-Lam coupling has evolved as a shining star among C-heteroatom coupling reactions because of its greener open flask chemistry and tremendous possibilities in terms of substrate bank, catalyst varieties, unlocking nature friendly conditions, etc.