Photodynamic Therapy with Photodegradable Photosensitizers

Photodegradable photosensitizers have gained significant attention in recent years to increase the safety of photodynamic therapy. Upon light exposure, these photosensitizers generate reactive oxygen species and undergo degrading which can reduce post-treatment drug residues. We highlight the recent development of photodegradable photosensitizers, addressing the challenges related to light absorption efficiency, toxicity of degradated products. Future outlook for photodegradable photosensitizers will also be discussed.