Double dehydrogenative coupling of amino alcohols with primary alcohols under Mn() catalysis

Double dehydrogenative coupling of amino alcohols with primary alcohols under Mn() catalysis

Herein, we unveil a method for synthesizing substituted pyrrole and pyrazine compounds via a double dehydrogenative coupling of amino alcohols with primary alcohols, facilitated by Mn( i )-PNP catalysis, which uniquely enables the simultaneous formation of C-C and C-N bonds. Herein, we unveil a meth...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2024-11, Vol.6 (92), p.1366-1369
Hauptverfasser: Sivakumar, Ganesan, Suresh, Abhijith Karattil, Padhy, Smruti Rekha, Balaraman, Ekambaram
Format: Artikel
Sprache:eng
Schlagworte:
Alcohols
Catalysis
Chemical bonds
Chemical synthesis
Dehydrogenation
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Zusammenfassung:Herein, we unveil a method for synthesizing substituted pyrrole and pyrazine compounds via a double dehydrogenative coupling of amino alcohols with primary alcohols, facilitated by Mn( i )-PNP catalysis, which uniquely enables the simultaneous formation of C-C and C-N bonds. Herein, we unveil a method for synthesizing substituted pyrrole and pyrazine compounds via a double dehydrogenative coupling of amino alcohols with primary alcohols, facilitated by Mn( i )-PNP catalysis, which uniquely enables the simultaneous formation of C-C and C-N bonds.
ISSN:1359-7345
1364-548X
1364-548X
DOI:10.1039/d4cc03595j