One-pot synthesis of functionalized bis(trifluoromethylated)benziodoxoles from iodine() precursors
Bis(trifluoromethylated)benziodoxoles (Bx) are broadly used cyclic hypervalent iodine reagents due to their stability and unique chemical properties. However, current methods to access them require several steps and long reaction times, making their synthesis tedious. Herein, a direct one-pot synthe...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2023-10, Vol.59 (84), p.12637-1264 |
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| container_title | Chemical communications (Cambridge, England) |
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| creator | Milzarek, Tobias M Ramirez, Nieves P Liu, Xing-Yu Waser, Jerome |
| description | Bis(trifluoromethylated)benziodoxoles (Bx) are broadly used cyclic hypervalent iodine reagents due to their stability and unique chemical properties. However, current methods to access them require several steps and long reaction times, making their synthesis tedious. Herein, a direct one-pot synthesis of bis(trifluoromethylated) Bx reagents from iodine(
i
) precursors is reported, enabling the synthesis of functionalized reagents.
A one-pot synthesis of bis(trifluoromethylated)benziodoxoles from iodine(
i
) precursors has been developed. This method tolerates multiple functional groups on both alkyne and aromatic backbone. |
| doi_str_mv | 10.1039/d3cc04525k |
| format | Article |
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i
) precursors is reported, enabling the synthesis of functionalized reagents.
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i
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i
) precursors is reported, enabling the synthesis of functionalized reagents.
A one-pot synthesis of bis(trifluoromethylated)benziodoxoles from iodine(
i
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i
) precursors is reported, enabling the synthesis of functionalized reagents.
A one-pot synthesis of bis(trifluoromethylated)benziodoxoles from iodine(
i
) precursors has been developed. This method tolerates multiple functional groups on both alkyne and aromatic backbone.</abstract><cop>Cambridge</cop><pub>Royal Society of Chemistry</pub><doi>10.1039/d3cc04525k</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0001-7512-9093</orcidid><orcidid>https://orcid.org/0000-0002-4570-914X</orcidid><orcidid>https://orcid.org/0000-0002-6888-9649</orcidid><orcidid>https://orcid.org/0000-0002-7434-4469</orcidid></addata></record> |
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| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2023-10, Vol.59 (84), p.12637-1264 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_crossref_primary_10_1039_D3CC04525K |
| source | Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| subjects | Chemical properties Chemical synthesis Iodine Precursors Reagents |
| title | One-pot synthesis of functionalized bis(trifluoromethylated)benziodoxoles from iodine() precursors |
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