One-pot synthesis of functionalized bis(trifluoromethylated)benziodoxoles from iodine() precursors
Bis(trifluoromethylated)benziodoxoles (Bx) are broadly used cyclic hypervalent iodine reagents due to their stability and unique chemical properties. However, current methods to access them require several steps and long reaction times, making their synthesis tedious. Herein, a direct one-pot synthe...
Gespeichert in:
Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2023-10, Vol.59 (84), p.12637-1264 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Bis(trifluoromethylated)benziodoxoles (Bx) are broadly used cyclic hypervalent iodine reagents due to their stability and unique chemical properties. However, current methods to access them require several steps and long reaction times, making their synthesis tedious. Herein, a direct one-pot synthesis of bis(trifluoromethylated) Bx reagents from iodine(
i
) precursors is reported, enabling the synthesis of functionalized reagents.
A one-pot synthesis of bis(trifluoromethylated)benziodoxoles from iodine(
i
) precursors has been developed. This method tolerates multiple functional groups on both alkyne and aromatic backbone. |
---|---|
ISSN: | 1359-7345 1364-548X |
DOI: | 10.1039/d3cc04525k |